ABSTRACT: The Saint Louis Zoo has a longstanding commitment to both in situ and ex situ conservation efforts for reptiles and amphibians across the globe. From the highlands of Western Asia to the streams of the Ozarks, the Zoo takes pride in being a conservation-focused institution. This presentation provides an overview of the Zoo's Herpetology department conservation initiatives, highlighting both local and international projects, with a focus on their in situ and ex situ contributions to the preservation of vital species.